Mito2
IHHT Staff Training Reference
Staff Use Only
🛑
Staff Training App — Important Notices
  • For staff use only. This app is a training and reference tool for Mito2 facility staff. It is not intended for clients/patients.
  • Not a substitute for medical care. IHHT therapy does not replace professional medical evaluation, diagnosis, or treatment.
  • Training prerequisite. Staff must complete Mito2 operator training before conducting client/patient sessions on the Mito2 system.
What Makes Each Phase Different?
The short answer: how long the body spends in the low-oxygen state each session. More time = stronger stimulus = deeper adaptation. That's it.
Phase 1
Adaptive Phase
16
minutes of low-oxygen exposure per session
The body learns to handle low-oxygen conditions. Everyone starts here — it's where we establish how your body responds before increasing the dose.
Cycles4 cycles
Low O₂ (oxygen drops)4 min
High O₂ (recovery)3 min
Total session time~28–35 min
How long4–8 weeks
How often2–3× per week
MovementStart with resting sessions. Movement introduced gradually based on client response and clinician discretion.
Phase 2
Conditioning Phase
20
minutes of low-oxygen exposure per session
The dose increases. The body is now handling the stimulus well, so we add more volume — one extra cycle adds 4 more minutes of low-oxygen time.
Cycles5 cycles
Low O₂ (oxygen drops)4 min
High O₂ (recovery)2 min
Total session time~35–40 min
How long4–6 weeks
How often2–3× per week
MovementStart with resting sessions. Movement introduced gradually based on client response and clinician discretion.
Phase 3
Optimized Phase
24
minutes of low-oxygen exposure per session
Maximum dose — the body has proven it's ready. Six cycles at full dose. Start with resting sessions. Movement introduced gradually based on client response and clinician discretion.
Cycles6 cycles
Low O₂4 min
High O₂3 min
Total session time~42–47 min
Movement / CardioStart with resting sessions. Movement introduced gradually based on client response and clinician discretion.
Every session delivers real benefits — no matter which phase or protocol the client/patient is on. These numbers show how their body is adapting so we can tailor the approach. Every person responds differently, and that's completely normal.
📋 After every session, walk the client/patient through this screen in 2–3 minutes. Tap any numbered card below to see what the number means, what to do, and what to say to the client/patient. 👆 Tap any card
🔄
Cells Adapting — 3 of 4 Metrics In Range
Every session is training your cells · Continue current protocol
MITO2
Session Complete
Adaptive Phase · 3 Cycles
1
⏱ Duration
13:22
Total session time
2
🔄 Cycles
3/3
Completed / Programmed
3
📈 Low Phase SpO₂
82%
Ideal zone
Min:80% Max:91% Target:82–88%
4
♡ Heart Rate
94 BPM
Low:108 High:83 Ceiling:132
Performance Metrics
5
📉 Time to Hypoxia
27s
Fast Response
C2:39s C3:43s Target:150s+
6
📈 Time to Recovery
17s
Strong
C1:17s C2:17s C3:17s Target:≤45s
7
🛡 Safety Events
0
Clean
Auto-switches · Target:0
8
📊 Your Session Snapshot
3 of 4 metrics in range — your cells are still adapting
Low Phase SpO₂
82%
82–88%
Time to Hypoxia
27s
150s+
Time to Recovery
17s
≤45s
Safety Events
0
≤1
All Metrics In Range — 4 of 4
Your cells are responding well · Clinician will review for phase progression
MITO2
Session Complete
Adaptive Phase · 4 Cycles
1
⏱ Duration
31:14
Total session time
2
🔄 Cycles
4/4
Completed / Programmed
3
📈 Low Phase SpO₂
84%
Ideal zone
Min:81% Max:90% Target:82–88%
4
♡ Heart Rate
88 BPM
Low:96 High:78 Ceiling:132
Performance Metrics
5
📉 Time to Hypoxia
128s
Passing
C2:124s C3:131s C4:128s Target:150s+
6
📈 Time to Recovery
22s
Strong
C1:20s C2:24s C3:21s C4:23s Target:≤30s
7
🛡 Safety Events
0
Clean
Auto-switches · Target:0
8
📊 Your Session Snapshot
All 4 metrics in range — your cells are handling oxygen efficiently
Low Phase SpO₂
84%
82–88%
Time to Hypoxia
128s
150s+
Time to Recovery
22s
≤30s
Safety Events
0
≤1
Every session delivers real benefits — no matter what these numbers say. These 4 measurements help us understand how each person's body is adapting. Some people respond quickly, some slowly — both are completely normal. The numbers guide the pace, not the value of the therapy.
Reading the Results
4 numbers on the session screen — here's what each one means, in plain English
📌 All 4 metrics use the same target ranges across every phase — Adaptive, Conditioning, and Optimized.
1
How Fast Oxygen Dropped
"This tells us how quickly your body enters the low-oxygen zone. Everyone's a little different — and no matter how fast or slow it happens, your cells are still getting the full benefit of the therapy."
📘 Staff context: Think of it like gas mileage. A body that holds on to available oxygen longer — under this challenge, on this day — is like a car that goes further on a tank of gas. A body that drops quickly burns through it faster. That's what this number reflects in this session, and it's what we track as the program progresses.
PASSING ✔
150 seconds or more
Controlled, steady drop. The body is entering hypoxia at a good pace.
→ Supports advancement when all 4 metrics pass consistently.
WATCH
60–119 seconds
Dropping a bit faster than ideal — common early on and usually improves over sessions.
→ Stay in current phase. Reassess over the next few sessions.
FAST RESPONSE
Under 60 seconds
Oxygen dropped quickly — very common early on and usually improves on its own. Not a problem.
→ Stay in current phase. Full benefits still happening. Does not block advancement if other 3 metrics pass.
⚠️ Cycle 1 always shows 0 seconds — this is just the sensor warming up, not a real reading. Always look at Cycles 2 and beyond.
2
Oxygen Level During Low Phase
"Think of this like a workout intensity level for your cells. We want it in a specific range — strong enough to trigger your body's natural healing response, but not more than it can handle comfortably right now."
📘 Staff context: Think of it like the effort level in a workout. Too little effort and you don't get much adaptation. Too much and you're working outside the intended zone. The machine tracks where the client/patient actually landed during the session so the protocol can be adjusted accordingly.
IDEAL ✔
82–88%
The sweet spot — strong enough to trigger adaptation, comfortable enough to sustain.
→ Supports advancement when consistent across sessions
MILD
89–90%
Session may be a little too easy to drive the best adaptation. Still beneficial — just gentler.
→ Stay at current level. Clinician may adjust settings.
TOO LOW
80–81% or below
Oxygen dropped further than intended. The dose may be too strong right now.
→ Do not advance. Flag for clinician review before next session.
82–88% is the target zone that activates the body's natural healing response without creating unnecessary stress on the system.
3
How Fast the Body Bounced Back
"Once the high-oxygen air kicks in, how quickly did your levels return to normal? This is the single best sign of how well your body is handling the sessions — and it almost always improves over time."
📘 Staff context: Think of it like recovery time between intervals in a workout. It's the body's bounce-back speed within this session — a useful indicator of where someone is starting from, and one of the metrics to watch as the program progresses.
STRONG ✔
45 seconds or less
Excellent bounce-back. The body is handling the session load very well.
→ Supports advancement when combined with other passing metrics
WATCH
46–60 seconds
Recovery is taking a bit longer — watch this over the next few sessions. Usually improves on its own.
→ Stay in current phase. Reassess in a few sessions.
SLOW
Over 60 seconds
Taking longer than expected. May also be a sensor placement issue — check that first.
→ Hold at current level. Check sensor. Flag for clinician if it continues.
This is the most reliable sign that a client/patient is ready to move to the next phase. If it's not improving after 4–6 sessions, let the clinician know.
4
Safety Check-Ins
"Zero means a perfectly smooth session — that's our target every time. If the system stepped in once during one of your cycles, that's perfectly fine — it's the built-in safety feature doing exactly what it's there for."
📘 Staff context: A safety event is not an alarm and it's not a sign the session failed — it's the machine responding in real time exactly as designed. Also worth knowing: pulse oximetry can be affected by circulation, skin temperature, or movement, so always look at the full picture. When in doubt, defer to the supervising clinician.
CLEAN ✔
0 check-ins
Session ran smoothly from start to finish. Ideal outcome every time.
→ Document normally. This is the target every session.
ACCEPTABLE
1 per cycle (or fewer)
The machine stepped in — one check-in per cycle is acceptable. The system is doing exactly what it's designed to do.
→ Acceptable. Stay at current level. Aim for 0 consistently before advancing.
REVIEW
More than 1 per cycle
The system is stepping in frequently. The current dose may be more than the body is ready for right now.
→ Do not advance. Let clinician know before the next session.
⭐ Never frame a safety check-in as something bad. Zero is the goal, but 1 per cycle is acceptable. Always say: "The system stepped in once during one of your cycles — that's perfectly fine."
✔ All Metrics In Range
All 4 numbers in range across 3 sessions in a row = eligible for phase review. Clinician confirms before any phase change.
🔄 Cells Adapting
One or more metrics still building. Stay in current phase. The client/patient is getting full therapeutic benefit every session — no exceptions.
🫁
Optional Assessment Tool
BOLT Score — Body Oxygen Level Test
A simple 2-minute breath-hold test that reveals how efficiently the body processes oxygen — and directly predicts what you'll see on the session screen. Highly recommended at intake and at each phase transition.
🔬
What It Measures
BOLT measures CO₂ tolerance — how well the body handles the natural build-up of carbon dioxide during normal breathing. This is not a test of lung capacity or fitness. It reflects the sensitivity of the breathing control center in the brain. A low score means the brain triggers the urge to breathe too early, before CO₂ has reached a useful level.
💡
Why It Matters for IHHT
IHHT works by training the body to handle oxygen more efficiently — the same system BOLT measures. A low BOLT score at intake almost always correlates with Fast Response on the session screen. As IHHT sessions accumulate and cells adapt, the BOLT score should rise. It's a simple outside-the-machine way to track the same progress the session screen shows inside it.
📋 How to Perform the BOLT Test
1
Sit quietly
Rest for 5–10 minutes. Normal relaxed posture.
2
Breathe normally
Take one normal breath in through the nose.
3
Exhale gently
Let a normal breath out through the nose. Do NOT force it.
4
Pinch & start timer
Pinch the nose closed. Start timing immediately.
5
First urge — stop
Stop the timer at the FIRST urge to breathe. Not maximum hold.
⚠️ Critical: This is NOT a maximum breath-hold competition. The measurement is taken at the first involuntary urge to breathe — the moment there's a slight tension or swallowing sensation. After releasing, breathing should return to normal within 2–3 breaths. If it doesn't, the hold was too long and the test should be repeated.
The Formula
Normal exhale →
BOLT = T seconds
→ First urge to breathe
Where T is the elapsed time in seconds between the end of the natural exhale and the first involuntary desire to inhale. No math required — the stopwatch value is the score.
Developed by Patrick McKeown, author of The Oxygen Advantage. Used clinically in breath re-training programs worldwide.
📊 Score Interpretation
≤10s
Very Low
Significant breathing dysfunction. Likely over-breathing chronically. Fast Response very probable.
11–20s
Below Average
Reduced CO₂ tolerance. Fast Response likely on session screen. Good candidate for IHHT.
21–30s
Moderate
Some breathing inefficiency. May show Watch zone (60–119s) on Time to Hypoxia.
31–40s
Good
Healthy CO₂ tolerance. Likely to show Passing zone on Time to Hypoxia early.
40s+
Excellent
Optimal oxygen utilization. Typical of trained athletes and long-term IHHT participants.
🔗 How BOLT Connects to the Session Screen
BOLT and Time to Hypoxia measure the same underlying system from two different angles. Use this table to set expectations before the first session — and to explain what the client/patient sees afterward.
BOLT Score Likely Time to Hypoxia What to Tell the Client/Patient IHHT Outlook
≤10 seconds Fast Response (<60s) "Your body is very sensitive to oxygen changes right now — that's exactly why IHHT is a great fit for you." Expect Fast Response early. Will improve noticeably with consistency.
11–20 seconds Fast Response or Watch "Your oxygen drops quickly at first — that's common and it almost always evens out on its own." Most clients/patients see TTH improvement within 4–8 sessions.
21–30 seconds Watch zone (60–119s) "Your response is in a normal range — your cells are adapting steadily." Likely to reach Passing zone within first phase.
31–40 seconds Passing (150s+) "Your breathing efficiency is already strong — we may see great numbers from early sessions." Strong starting position. Focus on SpO₂ and recovery metrics.
40+ seconds Passing from session 1 "Your body handles oxygen very efficiently — we'll be watching the other metrics to drive your progression." Optimal baseline. Phase progression likely to be faster.
📅 When to Test
1
Intake — before first session
Establishes baseline. Sets expectation for early session results. Helps explain Fast Response before it happens.
2
Phase transition — entering Conditioning
Confirms that CO₂ tolerance has improved alongside session metrics. Motivating for clients/patients to see progress.
3
Phase transition — entering Optimized
Full picture of adaptation progress. Comparison across all three measurements tells a compelling story.
📈 What Progress Looks Like
As IHHT sessions accumulate, expect to see BOLT scores improve alongside session metrics. A typical progression for a client/patient starting with poor breathing efficiency:
INTAKE
8s
Very Low
CONDITIONING
18s
Below Avg
OPTIMIZED
28s
Moderate
MAINTENANCE
38s
Good
🧬 The Science — Medium Depth
⚖️
CO₂ Tolerance
Most people believe the urge to breathe comes from low oxygen. It doesn't — it comes from rising CO₂. People with poor breathing habits have trained their brain to overreact to small CO₂ increases. BOLT measures how quickly that overreaction kicks in.
🔄
The Bohr Effect
CO₂ is what allows hemoglobin to actually release oxygen to the cells — this is called the Bohr Effect. If someone over-breathes and flushes out CO₂, their blood oxygen may look fine on a pulse oximeter, but the cells aren't receiving it efficiently. IHHT trains the body to tolerate the CO₂ levels needed for optimal oxygen delivery.
🎯
Why IHHT Improves BOLT
Each IHHT session exposes the body to controlled hypoxia — intentional low oxygen. Over time, this desensitizes the CO₂ receptors, increases red blood cell efficiency, and grows new blood vessels. The result is a body that handles oxygen and CO₂ fluctuations more calmly. BOLT rises. Time to Hypoxia rises with it.
Optional — But Highly Recommended
BOLT is not required to run IHHT sessions. The session screen gives you everything you need to manage protocol and progression. But adding BOLT at intake takes 2 minutes and gives you a powerful pre-session conversation tool — especially for explaining Fast Response before it surprises a client/patient. It also gives clients/patients something tangible to track outside the clinic. Consider adding it to your standard intake workflow.
What to Say
Ready-to-use scripts for every client/patient conversation — tap any card to expand

🧠 Protocol Advisor

Enter client/patient details below to receive an AI-generated session protocol recommendation tailored to their condition and profile.

🛑 Important — Please Read Before Continuing

The protocol recommendations generated by this tool are for informational and guidance purposes only. They are not a substitute for professional medical evaluation or clinical judgment. All session parameters must be reviewed and approved by a qualified clinician before use. Individual responses to IHHT vary — client/patient safety is always the primary consideration. Mito2 and its partners assume no liability for outcomes resulting from the use of these recommendations.

All clients/patients should begin on the Adaptive Phase unless a clinician has explicitly determined otherwise based on clinical assessment.

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